—  SPECIALTY CONFERENCE  — Gynecologic Pathology Wednesday, March 24, 2009, 7:30 PM Salon 2 Ovarian Cancer Moderator: ROBERT J. KURMAN Johns Hopkins Hospital, Baltimore, MD Disclosure: In accordance with ACCME guidelines regarding disclosure, the USCAP policy requires that faculty members who have a significant financial or other relationship with a commercial company, entity, or service (which will be discussed in this Symposium) must disclose this to attendees. The Academy also requires that speakers disclose any products that are not labeled for the use under discussion. The speakers listed below have indicated they have nothing to disclose. Panelists: PATRICIA A. SHAW, University of Toronto, Toronto, Ontario, Canada ELVIO SILVA, Anderson Cancer Center, Houston, TX; Cedars-Sinai Medical Center, Los Angeles, CA; Baylor Hospital, Dallas, TX KATHLEEN R. CHO, University of Michigan Medical School, Ann Arbor, MI IE-MING SHIH, Johns Hopkins University School of Medicine, Baltimore, MD Clinical histories are displayed below. For the fastest viewing of virtual slides, click: under each thumbnail image below. You must have Aperio ImageScope installed on your PC. If you do not already have Aperio ImageScope, Windows users with administrator privileges may download and install a free version in order to view USCAP Virtual Slides. Click the icon on the right to get your free copy:   Or, click on slide thumbnail images to view each slide in a Web-based slide viewer, which is somewhat slower. If you have any difficulties viewing these slides, email or call George Clay at +1.724.449.1137. Case 1 Submitted by: Patricia A. Shaw - Toronto General Hospital, Toronto, Ontario, Canada Clinical Summary: Modified radical hysterectomy, bilateral salpingo- oophorectomy and lymph node dissection is performed on a 56 year old woman with adenocarcinoma diagnosed on Pap smear and endocervical curettage. Case 1 - Figure 1 Case 1 - Figure 2 Case 1 - Figure 3 Case 2 Submitted by: Elvio Silva - Anderson Cancer Center, Houston, TX; Cedars-Sinai Medical Center, Los Angeles, CA; Baylor Hospital, Dallas, TX Clinical Summary: This is a 58 year old female who was diagnosed with an ovarian neoplasm in December 1997. Pertinent Laboratory Data: List of treatments: December 97 – Surgery – Toxol and CisPlatinin X6 June 2000 – Recurrence – Toxol and Hexalen July 2002 – Recurrence – Topotecan September 2002 – Doxcil, Hemcetavine December 2003 – BP 16 March 2004 – Tamoxifen July 2007 – Arymidex December 2007 – Pain medicine Case 2 - Figure 1 Case 2 - Figure 2 Case 3 Submitted by: Kathleen R. Cho - University of Michigan Medical School, Ann Arbor, MI Clinical History: 46 year old woman with strong family history of ovarian cancer and bilateral ovarian masses. Case 3 - Figure 1 Case 3 - Figure 2 Case 3 - Figure 3 Case 3 - Figure 4 Case 3 - Figure 5 Case 3 - Figure 6 Case 4 Submitted by: Ie-Ming Shih - Johns Hopkins University School of Medicine, Baltimore, MD Clinical Summary: A 42 y/o nulligravid Asian female presented with increasing intra-abdominal lymphadenopathy shortly after carboplatin/paclitaxel treatment for her previous "ovarian carcinoma" in an outside hospital. Unfortunately, the original tumor tissue was not available to review at that moment. She developed postoperative venous thromboembolism. Past history was significant for endometriosis. The sections were obtained from lymph node dissection. Case 4 - Figure 1 Case 4 - Figure 2 Case 4 - Figure 3 Handouts for all Specialty Conferences will be accessible via the "Educational Materials" section on the homepage the morning after each respective conference. Printed copies of the handout will not be available at the meeting.